Bilateral Ovarian Clear Cell Carcinoma Arising in 17 Year Longstanding History of Bilateral Ovarian Endometriosis

Authors

  • Mazita Ismail Dept. of Pathology, Hospital Raja Permaisuri Bainun, 30990 Ipoh, Perak, Malaysia
  • Nik Mohamed Zaki Nik Mahmood Dept. of Obstetrics and Gynaecology, School of Medical Sciences, Universiti Sains Malaysia,, 16150 Kubang Kerian, Kelantan, Malaysia
  • Saung Oo Ma Dept. of Obstetrics and Gynaecology, School of Medical Sciences, Universiti Sains Malaysia,, 16150 Kubang Kerian, Kelantan, Malaysia
  • Thin Thin Win Dept. of Pathology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
Abstract:

Clear cell carcinoma of ovary is uncommon ovarian tumour that arises from surface epithelium of ovary. It has well-known association with ovarian endometriosis. We report here the first case of bilateral clear cell carcinoma of ovaries in a 40-year-old woman with a 17-year history of bilateral ovarian endometriosis. In addition, during the longstanding duration of the endometriosis, the patient was treated with hormonal therapy, including oestrogen. It represents the first report of such bilateral involvement in the background of ovarian endometriosis. This should prompt clinicians to be aware that prolonged hormonal treatment of endometriosis may precipitate bilateral malignancy of the ovary.

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Journal title

volume 11  issue 5

pages  478- 482

publication date 2016-10-01

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